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Paired Primary and Metastatic Tumor Analysis of Somatic Mutations in Synchronous and Metachronous Colorectal Cancer

PURPOSE: Although the mutation status of KRAS is highly concordant in primary and metastatic lesions, it has not been generalized to other major pathway genes. MATERIALS AND METHODS: In this study, 41 genes were evaluated and the mutational profiles were compared in 46 colorectal cancer patients wit...

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Detalhes bibliográficos
Publicado no:Cancer Res Treat
Main Authors: Kim, Kyu-pyo, Kim, Jeong-Eun, Hong, Yong Sang, Ahn, Sung-Min, Chun, Sung Min, Hong, Seung-Mo, Jang, Se Jin, Yu, Chang Sik, Kim, Jin Cheon, Kim, Tae Won
Formato: Artigo
Idioma:Inglês
Publicado em: Korean Cancer Association 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5266409/
https://ncbi.nlm.nih.gov/pubmed/27384156
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4143/crt.2015.490
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