Oxidative Stress, Nrf2, and Epigenetic Modification Contribute to Anticancer Drug Resistance

Nuclear factor E2-related factor 2 (Nrf2), a transcription factor, controls the expression of genes encoding cytoprotective proteins, including antioxidant enzymes that combat oxidative and electrophilic stress to maintain redox homeostasis. However, recent studies demonstrated that, in cancer, aber...

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Bibliographic Details
Published in:Toxicol Res
Main Authors: Kang, Kyoung Ah, Hyun, Jin Won
Format: Artigo
Language:Inglês
Published: Korean Society of Toxicology 2017
Subjects:
Invited Review
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5266370/
https://ncbi.nlm.nih.gov/pubmed/28133507
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.5487/TR.2017.33.1.001
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