CD45RA Distinguishes CD4+CD25+CD127−/low TSDR Demethylated Regulatory T Cell Subpopulations With Differential Stability and Susceptibility to Tacrolimus-Mediated Inhibition of Suppression

BACKGROUND: Adoptive transfer of forkhead box protein (FOX)3(+) regulatory T (Treg) cells offers a promising strategy to reduce damage to an allograft by the recipient's immune system. Identification of cell surface markers sufficient to purify Treg cells expanded ex vivo to remove cellular con...

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Detalhes bibliográficos
Publicado no:Transplantation
Main Authors: Arroyo Hornero, Rebeca, Betts, Gareth J., Sawitzki, Birgit, Vogt, Katrin, Harden, Paul N., Wood, Kathryn J.
Formato: Artigo
Idioma:Inglês
Publicado em: Lippincott Williams & Wilkins 2017
Assuntos:
Original Basic Science—General
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5265687/
https://ncbi.nlm.nih.gov/pubmed/28118317
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/TP.0000000000001278
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