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Inhibition of sleep in rats by inorganic selenium compounds, inhibitors of prostaglandin D synthase.

Prostaglandin (PG) D2 has been postulated to be an endogenous sleep-promoting factor in rats, and SeCl4 and Na2SeO3 recently have been shown to inhibit the PGD synthase (prostaglandin-H2 D-isomerase, EC 5.3.99.2) activity of rat brain. The effect of these selenium compounds on sleep-wake activities...

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Détails bibliographiques
Publié dans:Proc Natl Acad Sci U S A
Auteurs principaux: Matsumura, H, Takahata, R, Hayaishi, O
Format: Artigo
Langue:Inglês
Publié: National Academy of Sciences 1991
Sujets:
Accès en ligne:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC52648/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1924366/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.88.20.9046
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