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PCNA dependent cellular activities tolerate dramatic perturbations in PCNA client interactions
Proliferating cell nuclear antigen (PCNA) is an essential cofactor for DNA replication and repair, recruiting multiple proteins to their sites of action. We examined the effects of the PCNA(S228I) mutation that causes PCNA-associated DNA repair disorder (PARD). Cells from individuals affected by PAR...
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| Publicado no: | DNA Repair (Amst) |
|---|---|
| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Elsevier
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5264654/ https://ncbi.nlm.nih.gov/pubmed/28073635 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.dnarep.2016.12.003 |
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