The role of miR-26a and miR-30b in HER2+ breast cancer trastuzumab resistance and regulation of the CCNE2 gene

A subset of HER2+ breast cancer patients manifest clinical resistance to trastuzumab. Recently, miR-26a and miR-30b have been identified as trastuzumab response regulators, and their target gene CCNE2 seems to play an important role in resistance to trastuzumab therapy. Cell viability was evaluated...

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Bibliografische gegevens
Gepubliceerd in:Sci Rep
Hoofdauteurs: Tormo, Eduardo, Adam-Artigues, Anna, Ballester, Sandra, Pineda, Begoña, Zazo, Sandra, González-Alonso, Paula, Albanell, Joan, Rovira, Ana, Rojo, Federico, Lluch, Ana, Eroles, Pilar
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Nature Publishing Group 2017
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Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5264595/
https://ncbi.nlm.nih.gov/pubmed/28120942
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep41309
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