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The role of miR-26a and miR-30b in HER2+ breast cancer trastuzumab resistance and regulation of the CCNE2 gene

A subset of HER2+ breast cancer patients manifest clinical resistance to trastuzumab. Recently, miR-26a and miR-30b have been identified as trastuzumab response regulators, and their target gene CCNE2 seems to play an important role in resistance to trastuzumab therapy. Cell viability was evaluated...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Sci Rep
Päätekijät: Tormo, Eduardo, Adam-Artigues, Anna, Ballester, Sandra, Pineda, Begoña, Zazo, Sandra, González-Alonso, Paula, Albanell, Joan, Rovira, Ana, Rojo, Federico, Lluch, Ana, Eroles, Pilar
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Nature Publishing Group 2017
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC5264595/
https://ncbi.nlm.nih.gov/pubmed/28120942
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep41309
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