BAP1 dependent expression of long non-coding RNA NEAT-1 contributes to sensitivity to gemcitabine in cholangiocarcinoma

BACKGROUND: Genetic alterations in chromatin modulators such as BRCA-1 associated protein-1 (BAP1) are the most frequent genetic alteration in intrahepatic cholangiocarcinomas (CCA). We evaluated the contribution of BAP1 expression on tumor cell behavior and therapeutic sensitivity to identify ratio...

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Vydáno v:Mol Cancer
Hlavní autoři: Parasramka, Mansi, Yan, Irene K., Wang, Xue, Nguyen, Phuong, Matsuda, Akiko, Maji, Sayantan, Foye, Catherine, Asmann, Yan, Patel, Tushar
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2017
Témata:
Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5264287/
https://ncbi.nlm.nih.gov/pubmed/28122578
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12943-017-0587-x
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