Transient receptor potential canonical 5 (TRPC5) protects against pain and vascular inflammation in arthritis and joint inflammation

OBJECTIVE: Transient receptor potential canonical 5 (TRPC5) is functionally expressed on a range of cells including fibroblast-like synoviocytes, which play an important role in arthritis. A role for TRPC5 in inflammation has not been previously shown in vivo. We investigated the contribution of TRP...

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Bibliografische gegevens
Gepubliceerd in:Ann Rheum Dis
Hoofdauteurs: Alawi, Khadija M, Russell, Fiona A, Aubdool, Aisah A, Srivastava, Salil, Riffo-Vasquez, Yanira, Baldissera, Lineu, Thakore, Pratish, Saleque, Nurjahan, Fernandes, Elizabeth S, Walsh, David A, Brain, Susan D
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: BMJ Publishing Group 2017
Onderwerpen:
Basic and Translational Research
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5264234/
https://ncbi.nlm.nih.gov/pubmed/27165180
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/annrheumdis-2015-208886
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