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WNT16 antagonises excessive canonical WNT activation and protects cartilage in osteoarthritis
OBJECTIVE: Both excessive and insufficient activation of WNT signalling results in cartilage breakdown and osteoarthritis. WNT16 is upregulated in the articular cartilage following injury and in osteoarthritis. Here, we investigate the function of WNT16 in osteoarthritis and the downstream molecular...
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| 出版年: | Ann Rheum Dis |
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| 主要な著者: | , , , , , , , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
BMJ Publishing Group
2017
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5264226/ https://ncbi.nlm.nih.gov/pubmed/27147711 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/annrheumdis-2015-208577 |
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