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WNT16 antagonises excessive canonical WNT activation and protects cartilage in osteoarthritis
OBJECTIVE: Both excessive and insufficient activation of WNT signalling results in cartilage breakdown and osteoarthritis. WNT16 is upregulated in the articular cartilage following injury and in osteoarthritis. Here, we investigate the function of WNT16 in osteoarthritis and the downstream molecular...
Gardado en:
| Publicado en: | Ann Rheum Dis |
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| Main Authors: | , , , , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
BMJ Publishing Group
2017
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5264226/ https://ncbi.nlm.nih.gov/pubmed/27147711 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/annrheumdis-2015-208577 |
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