Rapid generation of hypomorphic mutations

Hypomorphic mutations are a valuable tool for both genetic analysis of gene function and for synthetic biology applications. However, current methods to generate hypomorphic mutations are limited to a specific organism, change gene expression unpredictably, or depend on changes in spatial-temporal e...

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Publicado en:Nat Commun
Autores principales: Arthur, Laura L., Chung, Joyce J., Jankirama, Preetam, Keefer, Kathryn M., Kolotilin, Igor, Pavlovic-Djuranovic, Slavica, Chalker, Douglas L., Grbic, Vojislava, Green, Rachel, Menassa, Rima, True, Heather L., Skeath, James B., Djuranovic, Sergej
Formato: Artigo
Lenguaje:Inglês
Publicado: Nature Publishing Group 2017
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5263891/
https://ncbi.nlm.nih.gov/pubmed/28106166
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms14112
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