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Inter-residue distances derived from fold contact propensities correlate with evolutionary substitution costs

BACKGROUND: The wealth of information on protein structure has led to a variety of statistical analyses of the role played by individual amino acid types in the protein fold. In particular, the contact propensities between the various amino acids can be converted into folding energies that have prov...

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Bibliografiske detaljer
Main Authors: Williams, Gareth, Doherty, Patrick
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2004
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC526251/
https://ncbi.nlm.nih.gov/pubmed/15491497
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2105-5-153
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