Spatial patterning of P granules by RNA-induced phase separation of the intrinsically-disordered protein MEG-3

RNA granules are non-membrane bound cellular compartments that contain RNA and RNA binding proteins. The molecular mechanisms that regulate the spatial distribution of RNA granules in cells are poorly understood. During polarization of the C. elegans zygote, germline RNA granules, called P granules,...

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Publicat a:eLife
Autors principals: Smith, Jarrett, Calidas, Deepika, Schmidt, Helen, Lu, Tu, Rasoloson, Dominique, Seydoux, Geraldine
Format: Artigo
Idioma:Inglês
Publicat: eLife Sciences Publications, Ltd 2016
Matèries:
Cell Biology
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5262379/
https://ncbi.nlm.nih.gov/pubmed/27914198
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.21337
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