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Inhibition of Skp2 sensitizes lung cancer cells to paclitaxel

S-phase kinase-associated protein 2 (Skp2) is an E3 ubiquitin ligase and plays an important role in the control of cell cycle progression. Skp2 is upregulated in several cancers, including lung cancers, but the role of Skp2 in the tumorigenesis and anticancer drug resistance in human lung cancer rem...

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Библиографические подробности
Опубликовано в: :Onco Targets Ther
Главные авторы: Huang, Tonghai, Yang, Lin, Wang, Guangsuo, Ding, Guanggui, Peng, Bin, Wen, Yuxin, Wang, Zheng
Формат: Artigo
Язык:Inglês
Опубликовано: Dove Medical Press 2017
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC5261849/
https://ncbi.nlm.nih.gov/pubmed/28176922
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/OTT.S125789
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