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Inhibition of Skp2 sensitizes lung cancer cells to paclitaxel
S-phase kinase-associated protein 2 (Skp2) is an E3 ubiquitin ligase and plays an important role in the control of cell cycle progression. Skp2 is upregulated in several cancers, including lung cancers, but the role of Skp2 in the tumorigenesis and anticancer drug resistance in human lung cancer rem...
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Publicado no: | Onco Targets Ther |
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Main Authors: | , , , , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
Dove Medical Press
2017
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5261849/ https://ncbi.nlm.nih.gov/pubmed/28176922 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/OTT.S125789 |
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