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Inhibition of Skp2 sensitizes lung cancer cells to paclitaxel

S-phase kinase-associated protein 2 (Skp2) is an E3 ubiquitin ligase and plays an important role in the control of cell cycle progression. Skp2 is upregulated in several cancers, including lung cancers, but the role of Skp2 in the tumorigenesis and anticancer drug resistance in human lung cancer rem...

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Detalhes bibliográficos
Publicado no:Onco Targets Ther
Main Authors: Huang, Tonghai, Yang, Lin, Wang, Guangsuo, Ding, Guanggui, Peng, Bin, Wen, Yuxin, Wang, Zheng
Formato: Artigo
Idioma:Inglês
Publicado em: Dove Medical Press 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5261849/
https://ncbi.nlm.nih.gov/pubmed/28176922
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/OTT.S125789
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