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Inhibition of Skp2 sensitizes lung cancer cells to paclitaxel
S-phase kinase-associated protein 2 (Skp2) is an E3 ubiquitin ligase and plays an important role in the control of cell cycle progression. Skp2 is upregulated in several cancers, including lung cancers, but the role of Skp2 in the tumorigenesis and anticancer drug resistance in human lung cancer rem...
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| Publié dans: | Onco Targets Ther |
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| Auteurs principaux: | , , , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Dove Medical Press
2017
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5261849/ https://ncbi.nlm.nih.gov/pubmed/28176922 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/OTT.S125789 |
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