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CRTC1 Nuclear Translocation Following Learning Modulates Memory Strength via Exchange of Chromatin Remodeling Complexes on the Fgf1 Gene

Memory is formed by synapse-to-nucleus communication that leads to regulation of gene transcription, but the identity and organizational logic of signaling pathways involved in this communication remain unclear. Here we find that the transcription factor CRTC1 is a critical determinant of sustained...

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Detalles Bibliográficos
Publicado en:Cell Rep
Main Authors: Uchida, Shusaku, Teubner, Brett J.W., Hevi, Charles, Hara, Kumiko, Kobayashi, Ayumi, Dave, Rutu M., Shintaku, Tatsushi, Jaikhan, Pattaporn, Yamagata, Hirotaka, Suzuki, Takayoshi, Watanabe, Yoshifumi, Zakharenko, Stanislav S., Shumyatsky, Gleb P.
Formato: Artigo
Idioma:Inglês
Publicado: 2017
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5261823/
https://ncbi.nlm.nih.gov/pubmed/28076781
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2016.12.052
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