Effective Reduction in High Ethanol Drinking by Semi-synthetic Tetracycline Derivatives

BACKGROUND: New pharmacotherapies to treat Alcohol Use Disorders (AUD) are needed. Given the complex nature of AUD, there likely exist multiple novel drug targets. We, and others, have shown that the tetracycline drugs, minocycline and doxycycline, reduced ethanol drinking in mice. To test the hypot...

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Detalhes bibliográficos
Publicado no:Alcohol Clin Exp Res
Main Authors: Syapin, Peter J., Martinez, Joseph M., Curtis, David C., Marquardt, Patrick C., Allison, Clayton L., Groot, Jessica A., Baby, Carol, Al-Hasan, Yazan M., Segura, Ismael, Scheible, Matthew J., Nicholson, Katy T., Redondo, Jose Luis, Trotter, David R. M., Edwards, David S., Bergeson, Susan E.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5261821/
https://ncbi.nlm.nih.gov/pubmed/27859416
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/acer.13253
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