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Endochondral Ossification Is Accelerated in Cholinesterase-Deficient Mice and in Avian Mesenchymal Micromass Cultures

Most components of the cholinergic system are detected in skeletogenic cell types in vitro, yet the function of this system in skeletogenesis remains unclear. Here, we analyzed endochondral ossification in mutant murine fetuses, in which genes of the rate-limiting cholinergic enzymes acetyl- (AChE),...

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Pubblicato in:PLoS One
Autori principali: Spieker, Janine, Mudersbach, Thomas, Vogel-Höpker, Astrid, Layer, Paul G.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2017
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5261733/
https://ncbi.nlm.nih.gov/pubmed/28118357
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0170252
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