Plitidepsin: design, development, and potential place in therapy

Plitidepsin is a cyclic depsipeptide that was first isolated from a Mediterranean marine tunicate (Aplidium albicans) and, at present, is manufactured by total synthesis and commercialized as Aplidin(®). Its antitumor activity, observed in preclinical in vitro and in vivo studies has prompted numero...

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Bibliografiske detaljer
Udgivet i:Drug Des Devel Ther
Main Authors: Alonso-Álvarez, Sara, Pardal, Emilia, Sánchez-Nieto, Diego, Navarro, Miguel, Caballero, Maria Dolores, Mateos, Maria Victoria, Martín, Alejandro
Format: Artigo
Sprog:Inglês
Udgivet: Dove Medical Press 2017
Fag:
Review
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5261604/
https://ncbi.nlm.nih.gov/pubmed/28176904
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/DDDT.S94165
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