RanBP9/TSSC3 complex cooperates to suppress anoikis resistance and metastasis via inhibiting Src-mediated Akt signaling in osteosarcoma

Suppression of anoikis is a prerequisite for tumor cell metastasis, which is correlated with chemoresistance and poor prognosis. We characterized a novel interaction between RanBP9 SPRY domain and TSSC3 PH domain by which RanBP9/TSSC3 complex exerts transcription and post-translation regulation in o...

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Bibliografiske detaljer
Udgivet i:Cell Death Dis
Main Authors: Dai, Huanzi, Lv, Yang-Fan, Yan, Guang-Ning, Meng, Gang, Zhang, Xi, Guo, Qiao-Nan
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2016
Fag:
Original Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5261021/
https://ncbi.nlm.nih.gov/pubmed/28032865
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2016.436
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