Human umbilical cord blood-stem cells direct macrophage polarization and block inflammasome activation to alleviate rheumatoid arthritis

Rheumatoid arthritis (RA) is a long-lasting intractable autoimmune disorder, which has become a substantial public health problem. Despite widespread use of biologic drugs, there have been uncertainties in efficacy and long-term safety. Mesenchymal stem cells (MSCs) have been suggested as a promisin...

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Vydáno v:Cell Death Dis
Hlavní autoři: Shin, Tae-Hoon, Kim, Hyung-Sik, Kang, Tae-Wook, Lee, Byung-Chul, Lee, Hwa-Yong, Kim, Yoon-Jin, Shin, Ji-Hee, Seo, Yoojin, Won Choi, Soon, Lee, Seunghee, Shin, Kichul, Seo, Kwang-Won, Kang, Kyung-Sun
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group 2016
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Original Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5260999/
https://ncbi.nlm.nih.gov/pubmed/28005072
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2016.442
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