Phospholipase D1-regulated autophagy supplies free fatty acids to counter nutrient stress in cancer cells

Cancer cells utilize flexible metabolic programs to maintain viability and proliferation under stress conditions including nutrient deprivation. Here we report that phospholipase D1 (PLD1) participates in the regulation of metabolic plasticity in cancer cells. PLD1 activity is required for cancer ce...

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Bibliografische gegevens
Gepubliceerd in:Cell Death Dis
Hoofdauteurs: Cai, Ming, He, Jingquan, Xiong, Jian, Tay, Li Wei Rachel, Wang, Ziqing, Rog, Colin, Wang, Jingshu, Xie, Yizhao, Wang, Guobin, Banno, Yoshiko, Li, Feng, Zhu, Michael, Du, Guangwei
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Nature Publishing Group 2016
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Original Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5260880/
https://ncbi.nlm.nih.gov/pubmed/27809301
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2016.355
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