Endothelium-independent vasorelaxant effect of 20(S)-protopanaxadiol on isolated rat thoracic aorta

AIM: Ginsenosides are considered to be the major pharmacologically active ginseng constituents, whereas 20(S)-protopanaxadiol [20(S)-PPD] is the active metabolite of ginsenosides in gut. In this study we investigated the effect of 20(S)-PPD on isolated rat thoracic aortas as well as its vasorelaxant...

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Veröffentlicht in:Acta Pharmacol Sin
Hauptverfasser: Gan, Lu, Wang, Zhen-hua, Zhang, Hong, Zhou, Xin, Zhou, Hui, Sun, Chao, Si, Jing, Zhou, Rong, Ma, Cheng-jun, Li, Ji
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group 2016
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Original Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5260830/
https://ncbi.nlm.nih.gov/pubmed/27616575
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/aps.2016.74
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