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Rules of co-occurring mutations characterize the antigenic evolution of human influenza A/H3N2, A/H1N1 and B viruses

BACKGROUND: The human influenza viruses undergo rapid evolution (especially in hemagglutinin (HA), a glycoprotein on the surface of the virus), which enables the virus population to constantly evade the human immune system. Therefore, the vaccine has to be updated every year to stay effective. There...

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Publicado en:BMC Med Genomics
Main Authors: Chen, Haifen, Zhou, Xinrui, Zheng, Jie, Kwoh, Chee-Keong
Formato: Artigo
Idioma:Inglês
Publicado: BioMed Central 2016
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5260787/
https://ncbi.nlm.nih.gov/pubmed/28117657
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12920-016-0230-5
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