Mouse Erk-1 gene product is a serine/threonine protein kinase that has the potential to phosphorylate tyrosine.

Bacterial expression of mouse gene Erk-1 yielded an active kinase with the same substrate specificity shown for ERK1 protein purified from rat cells. Although rat gene ERK1 is believed to encode a serine/threonine kinase based on sequence data and known ERK1 substrate phosphorylation sites, bacteria...

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Publié dans:	Proc Natl Acad Sci U S A
Auteurs principaux:	Crews, C M, Alessandrini, A A, Erikson, R L
Format:	Artigo
Langue:	Inglês
Publié:	National Academy of Sciences 1991
Sujets:	Research Article
Accès en ligne:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC52607/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1717989/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.88.19.8845
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