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Long-term exposure to bisphenol A or benzo(a)pyrene alters the fate of human mammary epithelial stem cells in response to BMP2 and BMP4, by pre-activating BMP signaling

Bone morphogenetic protein 2 (BMP2) and BMP4 are key regulators of the fate and differentiation of human mammary epithelial stem cells (SCs), as well as of their niches, and are involved in breast cancer development. We established that MCF10A immature mammary epithelial cells reliably reproduce the...

תיאור מלא

שמור ב:
מידע ביבליוגרפי
הוצא לאור ב:Cell Death Differ
Main Authors: Clément, Flora, Xu, Xinyi, Donini, Caterina F, Clément, Alice, Omarjee, Soleilmane, Delay, Emmanuel, Treilleux, Isabelle, Fervers, Béatrice, Le Romancer, Muriel, Cohen, Pascale A, Maguer-Satta, Véronique
פורמט: Artigo
שפה:Inglês
יצא לאור: Nature Publishing Group 2017
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC5260492/
https://ncbi.nlm.nih.gov/pubmed/27740625
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cdd.2016.107
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