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Global inference of disease-causing single nucleotide variants from exome sequencing data

BACKGROUND: Whole exome sequencing (WES) has recently emerged as an effective approach for identifying genetic variants underlying human diseases. However, considerable time and labour is needed for careful investigation of candidate variants. Although filtration based on population frequencies and...

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Detalhes bibliográficos
Publicado no:BMC Bioinformatics
Main Authors: Wu, Mengmeng, Chen, Ting, Jiang, Rui
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5260102/
https://ncbi.nlm.nih.gov/pubmed/28155632
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12859-016-1325-x
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