Pharmacological investigation on the anti-oxidant and anti-inflammatory activity of N-acetylcysteine in an ex vivo model of COPD exacerbation

BACKGROUND: Oxidative stress is recognized to be one of predisposing factor in the pathogenesis of COPD. The oxidant/antioxidant imbalance is significantly pronounced in patients with COPD exacerbation. N-acetylcysteine (NAC) seems to be able to reduce COPD exacerbations by modulating the oxidative...

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Veröffentlicht in:Respir Res
Hauptverfasser: Cazzola, Mario, Calzetta, Luigino, Facciolo, Francesco, Rogliani, Paola, Matera, Maria Gabriella
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2017
Schlagworte:
Research
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5260037/
https://ncbi.nlm.nih.gov/pubmed/28118826
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12931-016-0500-y
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