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Sig2GRN: a software tool linking signaling pathway with gene regulatory network for dynamic simulation

BACKGROUND: Linking computational models of signaling pathways to predicted cellular responses such as gene expression regulation is a major challenge in computational systems biology. In this work, we present Sig2GRN, a Cytoscape plugin that is able to simulate time-course gene expression data give...

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Veröffentlicht in:BMC Syst Biol
Hauptverfasser: Zhang, Fan, Liu, Runsheng, Zheng, Jie
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2016
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5259907/
https://ncbi.nlm.nih.gov/pubmed/28155685
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12918-016-0365-1
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