Predicting MoRFs in protein sequences using HMM profiles

BACKGROUND: Intrinsically Disordered Proteins (IDPs) lack an ordered three-dimensional structure and are enriched in various biological processes. The Molecular Recognition Features (MoRFs) are functional regions within IDPs that undergo a disorder-to-order transition on binding to a partner protein...

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Udgivet i:BMC Bioinformatics
Main Authors: Sharma, Ronesh, Kumar, Shiu, Tsunoda, Tatsuhiko, Patil, Ashwini, Sharma, Alok
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2016
Fag:
Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5259822/
https://ncbi.nlm.nih.gov/pubmed/28155710
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12859-016-1375-0
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