Chemically-activatable alkyne-tagged probe for imaging microdomains in lipid bilayer membranes

A chemically-activatable alkynyl steroid analogue probe has been synthesized for visualizing the lipid raft membrane domains by Raman microscopy. The Raman probe, in which ring A of its steroid backbone is replaced with an alkynyl group, was designed to enable activation of the alkyne signal through...

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Udgivet i:Sci Rep
Main Authors: Yamaguchi, Satoshi, Matsushita, Taku, Izuta, Shin, Katada, Sumika, Ura, Manami, Ikeda, Taro, Hayashi, Gosuke, Suzuki, Yuta, Kobayashi, Koya, Tokunaga, Kyoya, Ozeki, Yasuyuki, Okamoto, Akimitsu
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2017
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5259774/
https://ncbi.nlm.nih.gov/pubmed/28117375
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep41007
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