Functional PTGS2 polymorphism-based models as novel predictive markers in metastatic renal cell carcinoma patients receiving first-line sunitinib

Sunitinib is the currently standard treatment for metastatic renal cell carcinoma (mRCC). Multiple candidate predictive biomarkers for sunitinib response have been evaluated but none of them has been implemented in the clinic yet. The aim of this study was to analyze single nucleotide polymorphisms...

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Vydáno v:Sci Rep
Hlavní autoři: Cebrián, Arancha, Gómez del Pulgar, Teresa, Méndez-Vidal, María José, Gonzálvez, María Luisa, Lainez, Nuria, Castellano, Daniel, García-Carbonero, Iciar, Esteban, Emilio, Sáez, Maria Isabel, Villatoro, Rosa, Suárez, Cristina, Carrato, Alfredo, Munárriz-Ferrándiz, Javier, Basterrechea, Laura, García-Alonso, Mirta, González-Larriba, José Luis, Perez-Valderrama, Begoña, Cruz-Jurado, Josefina, González del Alba, Aránzazu, Moreno, Fernando, Reynés, Gaspar, Rodríguez-Remírez, María, Boni, Valentina, Mahillo-Fernández, Ignacio, Martin, Yolanda, Viqueira, Andrea, García-Foncillas, Jesús
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group 2017
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5259767/
https://ncbi.nlm.nih.gov/pubmed/28117391
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep41371
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