Costunolide and dehydrocostuslactone combination treatment inhibit breast cancer by inducing cell cycle arrest and apoptosis through c-Myc/p53 and AKT/14-3-3 pathway

Our previous studies demonstrated that volatile oil from saussurea lappa root (VOSL), rich in two natural sesquiterpene lactones, costunolide (Cos) and dehydrocostuslactone (Dehy), exerts better anti-breast cancer efficacy and lower side effects than Cos or Dehy alone in vivo, however, their anti-ca...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Sci Rep
Päätekijät: Peng, Zhangxiao, Wang, Yan, Fan, Jianhui, Lin, Xuejing, Liu, Chunying, Xu, Yang, Ji, Weidan, Yan, Chao, Su, Changqing
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Nature Publishing Group 2017
Aiheet:
Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC5259746/
https://ncbi.nlm.nih.gov/pubmed/28117370
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep41254
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