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Retransformation of a simian virus 40 revertant cell line, which is resistant to viral and DNA infections, by microinjection of viral DNA.

We have isolated morphological transformants of cultured cells as dense foci on a monolayer of normal cells appproximately 4 weeks after microinjection of purified simian virus 40 DNA (200 to 400 molecules per cell) directly into the nucleus. Both Rat 1 (an established contact-inhibited rat embryo f...

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Main Authors: Graessmann, A, Graessmann, M, Topp, W C, Botchan, M
Formato: Artigo
Idioma:Inglês
Publicado: 1979
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC525948/
https://ncbi.nlm.nih.gov/pubmed/229275
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