In vivo catalysis of a metabolically essential reaction by an antibody.
We have established a growth selection requirement for a catalytic antibody with modest chorismate mutase activity. Conversion of (-)-chorismate into prephenate is the key step in the biosynthesis of the aromatic amino acids tyrosine and phenylalanine. Strains of the yeast Saccharomyces cerevisiae c...
Shranjeno v:
| izdano v: | Proc Natl Acad Sci U S A |
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| Principais autores: | , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
National Academy of Sciences
1991
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC52594/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1924339/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.88.19.8784 |
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