Inactivation of influenza and vesicular stomatitis virion RNA polymerase activities by photoreaction with 4'-substituted psoralens.

Irradiation of purified influenza virus and vesicular stomatitis virus (VSV) with long-wavelength UV light in the presence of 4'-substituted psoralens inactivated the virion-associated RNA polymerase activity. Inactivation was apparently due to psoralen modification of the viral genome RNAs, si...

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Bibliographic Details
Main Authors: Nakashima, K, Chanda, P K, Deutsch, V, Banerjee, A K, Shatkin, A J
Format: Artigo
Language:Inglês
Published: 1979
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC525932/
https://ncbi.nlm.nih.gov/pubmed/229269
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