Self-immolative nanoparticles for simultaneous delivery of microRNA and targeting of polyamine metabolism in combination cancer therapy

Combination of anticancer drugs with therapeutic miRNA has emerged as a promising anticancer strategy. However, the promise is hampered by a lack of desirable delivery systems. We report on the development of self-immolative nanoparticles capable of simultaneously delivering miR-34a mimic and target...

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Bibliographic Details
Published in:J Control Release
Main Authors: Xie, Ying, Murray-Stewart, Tracy, Wang, Yazhe, Yu, Fei, Li, Jing, Marton, Laurence J., Casero, Robert A., Oupický, David
Format: Artigo
Language:Inglês
Published: 2016
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5258827/
https://ncbi.nlm.nih.gov/pubmed/28017891
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jconrel.2016.12.017
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