P2X Receptors Inhibit NaCl Absorption in mTAL Independently of Nitric Oxide

Activation of basolateral P2X receptors markedly reduces NaCl absorption in mouse medullary thick ascending limb (mTAL). Here we tested the role of nitric oxide (NO) in the ATP-mediated (P2X) transport inhibition. We used isolated, perfused mTALs from mice to electrically measure NaCl absorption. By...

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Udgivet i:Front Physiol
Main Authors: Svendsen, Samuel L., Isidor, Søren, Praetorius, Helle A., Leipziger, Jens
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2017
Fag:
Physiology
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5258741/
https://ncbi.nlm.nih.gov/pubmed/28174542
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphys.2017.00018
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