Trim32 deficiency enhances Th2 immunity and predisposes to features of atopic dermatitis

Altered innate immunity is a feature of certain skin inflammatory diseases such as psoriasis and atopic dermatitis (AD). In this study, we provide evidence that deficiency in Trim32 (a tripartite motif (TRIM) protein with innate antiviral activity) contributes to a Th2 biased response and predispose...

Full description

Saved in:
Bibliographic Details
Published in:J Invest Dermatol
Main Authors: Liu, Yuangang, Wang, Zhiping, De La Torre, Rachel, Barling, Ashley, Tsujikawa, Takahiro, Hornick, Noah, Hanifin, Jon, Simpson, Eric, Wang, Yun, Swanzey, Emily, Wortham, Aaron, Ding, Hao, Coussens, Lisa M., Kulesz-Martin, Molly
Format: Artigo
Language:Inglês
Published: 2016
Subjects:
Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5258687/
https://ncbi.nlm.nih.gov/pubmed/27720760
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jid.2016.09.020
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items