Intraoperative cerebral oxygenation, oxidative injury, and delirium following cardiac surgery

BACKGROUND: Delirium affects 20–30% of patients after cardiac surgery and is associated with increased mortality and persistent cognitive decline. Hyperoxic reperfusion of ischemic tissues increases oxidative injury, but oxygen administration remains high during cardiac surgery. We tested the hypoth...

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Pubblicato in:Free Radic Biol Med
Autori principali: Lopez, Marcos G., Pandharipande, Pratik, Morse, Jennifer, Shotwell, Matthew S., Milne, Ginger L., Pretorius, Mias, Shaw, Andrew D., Roberts, L. Jackson, Billings IV, Frederic T.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2016
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5258679/
https://ncbi.nlm.nih.gov/pubmed/28039082
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.freeradbiomed.2016.12.039
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