Keratinocyte-derived chemokines orchestrate T cell positioning in the epidermis during vitiligo and may serve as biomarkers of disease

Vitiligo is an autoimmune disease of the skin that results in the destruction of melanocytes and the clinical appearance of white spots. Disease pathogenesis depends on IFN-γ and IFN-γ-induced chemokines to promote T cell recruitment to the epidermis where melanocytes reside. The skin is a complex o...

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Veröffentlicht in:J Invest Dermatol
Hauptverfasser: Richmond, Jillian M., Bangari, Dinesh S., Essien, Kingsley I., Currimbhoy, Sharif D., Groom, Joanna R., Pandya, Amit G., Youd, Michele E., Luster, Andrew D., Harris, John E.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2016
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5258673/
https://ncbi.nlm.nih.gov/pubmed/27686391
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jid.2016.09.016
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