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Induction of plasmacytomas secreting antigen-specific monoclonal antibodies with a retrovirus expressing v-abl and c-myc.

ABL-MYC, a recombinant murine retrovirus that expresses v-abl and c-myc, rapidly induces transplantable mono- or oligoclonal plasmacytomas in BALB/c mice. To determine if the targets for transformation of this retrovirus are antigen-committed B lymphocytes and to explore this system as an alternativ...

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Published in:Proc Natl Acad Sci U S A
Main Authors: Weissinger, E M, Mischak, H, Largaespada, D A, Kaehler, D A, Mitchell, T, Smith-Gill, S J, Risser, R, Mushinski, J F
Format: Artigo
Language:Inglês
Published: National Academy of Sciences 1991
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Research Article
Online Access:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC52584/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1924333/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.88.19.8735
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