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α-Iso-Cubebene Inhibits PDGF-Induced Vascular Smooth Muscle Cell Proliferation by Suppressing Osteopontin Expression

α-Iso-cubebene (ICB) is a dibenzocyclooctadiene lignin contained in Schisandra chinensis (SC), a well-known medicinal herb that ameliorates cardiovascular symptoms. Thus, we examined the effect of ICB on vascular smooth muscle cell (VSMC) proliferation, a key feature of diverse vascular diseases. Wh...

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Bibliografske podrobnosti
izdano v:PLoS One
Main Authors: Jang, Min A., Lee, Seung Jin, Baek, Seung Eun, Park, So Youn, Choi, Young Whan, Kim, Chi Dae
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2017
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5256966/
https://ncbi.nlm.nih.gov/pubmed/28114367
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0170699
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