Proteomic Analysis of Kveim Reagent Identifies Targets of Cellular Immunity in Sarcoidosis

BACKGROUND: Kveim-reagent (Kv) skin testing was a historical method of diagnosing sarcoidosis. Intradermal injection of treated sarcoidosis spleen tissue resulted in a granuloma response at injection site by 4–6 weeks. Previous work indicates proteins as the possible trigger of this reaction. We aim...

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Udgivet i:PLoS One
Main Authors: Eberhardt, Christian, Thillai, Muhunthan, Parker, Robert, Siddiqui, Nazneen, Potiphar, Lee, Goldin, Rob, Timms, John F., Wells, Athol U., Kon, Onn M., Wickremasinghe, Melissa, Mitchell, Donald, Weeks, Mark E., Lalvani, Ajit
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2017
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5256960/
https://ncbi.nlm.nih.gov/pubmed/28114394
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0170285
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