Scalable Parameter Estimation for Genome-Scale Biochemical Reaction Networks

Mechanistic mathematical modeling of biochemical reaction networks using ordinary differential equation (ODE) models has improved our understanding of small- and medium-scale biological processes. While the same should in principle hold for large- and genome-scale processes, the computational method...

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Bibliographic Details
Published in:PLoS Comput Biol
Main Authors: Fröhlich, Fabian, Kaltenbacher, Barbara, Theis, Fabian J., Hasenauer, Jan
Format: Artigo
Language:Inglês
Published: Public Library of Science 2017
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5256869/
https://ncbi.nlm.nih.gov/pubmed/28114351
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1005331
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