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The human L1 promoter: Variable transcription initiation sites and a major impact of upstream flanking sequence on promoter activity
Human L1 elements are non-LTR retrotransposons that comprise ∼17% of the human genome. Their 5′-untranslated region (5′-UTR) serves as a promoter for L1 transcription. Now we find that transcription initiation sites are not restricted to nucleotide +1 but vary considerably in both downstream and ups...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Cold Spring Harbor Laboratory Press
2004
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC525683/ https://ncbi.nlm.nih.gov/pubmed/15520289 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.2745804 |
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