A soluble, single-chain T-cell receptor fragment endowed with antigen-combining properties.

A strategy for the production of small, soluble, single-chain T-cell receptor (scTCR) fragments that carry an intact TCR antigen-combining site is presented. The rationale is based on structural similarity between TCR and antibody molecules and use of computer modeling methods to derive a model stru...

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Detalhes bibliográficos

Publicado no:	Proc Natl Acad Sci U S A
Principais autores:	Novotny, J, Ganju, R K, Smiley, S T, Hussey, R E, Luther, M A, Recny, M A, Siliciano, R F, Reinherz, E L
Formato:	Artigo
Idioma:	Inglês
Publicado em:	National Academy of Sciences 1991
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC52566/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1924326/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.88.19.8646
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