טוען...
Colonic microbiota can promote rapid local improvement of murine colitis by thioguanine independently of T lymphocytes and host metabolism
OBJECTIVE: Mercaptopurine (MP) and pro-drug azathioprine are ‘first-line’ oral therapies for maintaining remission in IBD. It is believed that their pharmacodynamic action is due to a slow cumulative decrease in activated lymphocytes homing to inflamed gut. We examined the role of host metabolism, l...
שמור ב:
הוצא לאור ב: | Gut |
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Main Authors: | , , , , , , , , , , , , , , , , |
פורמט: | Artigo |
שפה: | Inglês |
יצא לאור: |
BMJ Publishing Group
2017
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נושאים: | |
גישה מקוונת: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5256391/ https://ncbi.nlm.nih.gov/pubmed/27411368 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/gutjnl-2015-310874 |
תגים: |
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