Enzymatic modification of proteins with a geranylgeranyl isoprenoid.
The prenylation of several proteins involved in oncogenesis and signal transduction plays an essential role in regulating their biological activities. Two distinct isoprenoids are known to be involved in this modification, the 15-carbon farnesyl and 20-carbon geranylgeranyl groups. Thus far, identif...
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| Publicado no: | Proc Natl Acad Sci U S A |
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| Principais autores: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
1991
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC52563/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1924324/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.88.19.8631 |
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