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Adenylate cyclase A acting on PKA mediates induction of stalk formation by cyclic diguanylate at the Dictyostelium organizer

Coordination of cell movement with cell differentiation is a major feat of embryonic development. The Dictyostelium stalk always forms at the organizing tip, by a mechanism that is not understood. We previously reported that cyclic diguanylate (c-di-GMP), synthesized by diguanylate cyclase A (DgcA),...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Chen, Zhi-Hui, Singh, Reema, Cole, Christian, Lawal, Hajara Mohammed, Schilde, Christina, Febrer, Melanie, Barton, Geoffrey J., Schaap, Pauline
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5255622/
https://ncbi.nlm.nih.gov/pubmed/28057864
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1608393114
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